Which neurotransmitter is primarily responsible for inhibiting aggressive behavior?

Prepare for the American Board of Psychiatry and Neurology Exam. Practice with questions and detailed explanations to boost your confidence. Ensure your readiness for the big day!

Serotonin plays a crucial role in regulating mood and behavior, including aggression. Research has shown that lower levels of serotonin in the brain are associated with increased aggressive behavior. This neurotransmitter is involved in inhibiting impulsive responses and promoting social behavior. When serotonin levels are balanced and functioning well, they help to regulate emotions and promote feelings of calmness and well-being, which can mitigate aggressive impulses.

In contrast, elevated dopamine and norepinephrine are often linked to heightened alertness and arousal, which can increase aggressive tendencies under certain conditions. Aspartate primarily functions as an excitatory neurotransmitter in the central nervous system and does not have a direct role in inhibiting aggression. Thus, while serotonin acts to inhibit aggressive behavior, the other neurotransmitters may contribute to impulsivity and increased aggression in different contexts.

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