American Board of Psychiatry and Neurology (ABPN) Practice Exam

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Prepare for the American Board of Psychiatry and Neurology Exam. Practice with questions and detailed explanations to boost your confidence. Ensure your readiness for the big day!

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At what age is a patient most likely to develop tardive dyskinesia when on neuroleptic medications?

A. 25 years
B. 35 years
C. 45 years
D. 65 years

The correct answer is: D. 65 years

Tardive dyskinesia is a movement disorder that often occurs as a side effect of long-term use of neuroleptic medications, particularly antipsychotics. The risk of developing tardive dyskinesia increases with age, making older adults particularly vulnerable. In this context, patients aged 65 years and older are at the highest risk for developing tardive dyskinesia due to neuroleptic treatment. The mechanisms underlying this increased susceptibility in older populations include age-related changes in the brain and possibly greater cumulative exposure to these medications over time. Younger patients, such as those in their 25s, 35s, or 45s, generally have a lower incidence of this side effect. Though tardive dyskinesia can occur at any age, the likelihood escalates significantly in older individuals who have been on neuroleptic medications for extended periods.